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FR-05 · Program · Worldwide Clinical Trials · 2021–2026

Email security for regulated data

Roughly 200 gateway policies, authenticated mail, a closed bypass, and phishing triage with the SOC.

active Mimecast policies
about 200
policy categories
more than 35
of phishing reports triaged each month
hundreds

Context

Email carried PHI, PII, and clinical-trial data for a global clinical research organization under HIPAA. It was also where phishing arrived.

Constraints

  • Regulated data in outbound mail had to be caught by DLP.
  • Sender authentication had to hold for every domain in the tenant.
  • Hundreds of user-reported messages a month had to be triaged with the SOC.

What I did

  1. Administered roughly 200 Mimecast policies across more than 35 categories, including DLP for PHI, PII, and clinical-trial data.
  2. Enforced DMARC, SPF, and DKIM tenant-wide.
  3. Closed a mail-flow bypass that let senders deliver straight to the tenant endpoint around the Mimecast gateway.
  4. Worked phishing triage, message-trace forensics, and quarantine with the SOC, and ran Defender for Office 365 investigations to remove malicious mail and senders.

Outcome

Outbound mail ran through DLP policies for regulated data, inbound mail could no longer skip the gateway, and user-reported phishing had a working triage path with the SOC.

Takeaway

A gateway only protects the mail that actually passes through it.

Field Notes

Tags

  • Mimecast
  • DLP
  • DMARC
  • Defender for Office 365
  • HIPAA

Recon log

Findings 0/46

0/16 behavior and secret eggs. Hardware finds depend on the machine you visit from.

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Display0/7

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    rare

    Hint: Visit on a very large display.

  • Undiscovered (not found yet)

    uncommon

    Hint: Some monitors are wider than others.

  • Undiscovered (not found yet)

    uncommon

    Hint: Two screens are better than one.

  • Undiscovered (not found yet)

    rare

    Hint: Turn a monitor on its side.

  • Undiscovered (not found yet)

    common

    Hint: Pixels per inch matter.

  • Undiscovered (not found yet)

    uncommon

    Hint: Faster than 60 frames a second.

  • Undiscovered (not found yet)

    common

    Hint: Colors beyond sRGB.

Hardware0/11

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    rare

    Hint: Bring a flagship graphics card.

  • Undiscovered (not found yet)

    legendary

    Hint: A GPU that lives in a rack.

  • Undiscovered (not found yet)

    common

    Hint: A Mac with Apple silicon.

  • Undiscovered (not found yet)

    rare

    Hint: A Windows machine built for heavy work.

  • Undiscovered (not found yet)

    rare

    Hint: A Mac built for heavy work.

  • Undiscovered (not found yet)

    rare

    Hint: Two dozen threads or more.

  • Undiscovered (not found yet)

    rare

    Hint: Windows, but not on x86.

  • Undiscovered (not found yet)

    uncommon

    Hint: The year of the Linux desktop.

  • Undiscovered (not found yet)

    uncommon

    Hint: A laptop that boots straight into a browser.

  • Undiscovered (not found yet)

    uncommon

    Hint: No graphics card at all.

  • Undiscovered (not found yet)

    common

    Hint: A laptop you can poke.

Environment0/11

  • Undiscovered (not found yet)

    uncommon

    Hint: Visit while your battery is nearly flat.

  • Undiscovered (not found yet)

    uncommon

    Hint: Your browser has a setting for saving data.

  • Undiscovered (not found yet)

    uncommon

    Hint: Visit very late at night.

  • Undiscovered (not found yet)

    common

    Hint: Visit on a day off.

  • Undiscovered (not found yet)

    uncommon

    Hint: A browser with a lion on it.

  • Undiscovered (not found yet)

    common

    Hint: A browser with a fox on it.

  • Undiscovered (not found yet)

    uncommon

    Hint: An accessibility setting that calms things down.

  • Undiscovered (not found yet)

    uncommon

    Hint: Tell websites not to track you.

  • Undiscovered (not found yet)

    rare

    Hint: Visit from the Lone Star State.

  • Undiscovered (not found yet)

    common

    Hint: A newer version of HTTP.

  • Undiscovered (not found yet)

    rare

    Hint: A very narrow window.

Behavior0/7

  • Undiscovered (not found yet)

    uncommon

    Hint: Drag the edge of your browser window around.

  • Undiscovered (not found yet)

    uncommon

    Hint: Reach the bottom of the page quickly.

  • Undiscovered (not found yet)

    uncommon

    Hint: Try printing this page.

  • Undiscovered (not found yet)

    common

    Hint: Toggle the theme a few times.

  • Undiscovered (not found yet)

    rare

    Hint: Lose your connection.

  • Undiscovered (not found yet)

    rare

    Hint: Plug in a controller and press a button.

  • Undiscovered (not found yet)

    uncommon

    Hint: Sign the guestbook.

Secrets0/10

  • Undiscovered (not found yet)

    rare

    Hint: A famous cheat code.

  • Undiscovered (not found yet)

    common

    Hint: There's a terminal in here somewhere.

  • Undiscovered (not found yet)

    uncommon

    Hint: Ask the terminal about your machine.

  • Undiscovered (not found yet)

    uncommon

    Hint: Ask the terminal for root.

  • Undiscovered (not found yet)

    rare

    Hint: sudo, but make it a job offer.

  • Undiscovered (not found yet)

    rare

    Hint: The most dangerous command there is.

  • Undiscovered (not found yet)

    legendary

    Hint: Open your browser's developer console.

  • Undiscovered (not found yet)

    uncommon

    Hint: Click the logo. Then keep clicking.

  • Undiscovered (not found yet)

    legendary

    Hint: Type the 82nd's favorite word anywhere on the page.

  • Undiscovered (not found yet)

    legendary

    Hint: Find every egg that doesn't depend on your hardware.

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